Studies on Low Level Light Therapy (LLLT)
Here you can find links to research projects conducted into the effectiveness of low light therapy as a treatment for a variety of conditions.
In summary, laser therapy normalizes our body’s cellular functions by restoring disabled mitochondrial ATP production. This in turn leads to a cascade of processes that increases the recovery of damaged or poorly functioning tissue. The main categories of recovery are:
- Nerve Function (stimulation, healing, and pain reduction)
- Inflammation (takes the chronic inflammation into the acute phase)
- Wound Healing(inflammation, proliferation, maturation)
- Circulation (vasodilation and microcirculation)
Here is the list of research backed evidence to support the use of Low Light Therpay…
Blue Light Destroys Antibiotic Resistant Staph Infection
The Role of Nitric Oxide Insufficiency In Ageing & Disease
By Nathan S. Bryan, PhD.
Low level light effects on inflammatory cytokine production by rheumatoid arthritis synoviocytes.
Yamaura M, Yao M, Yaroslavsky I, Cohen R, Smotrich M, Kochevar IE
Acute Low Back Pain with Radiculopathy: A Double-Blind, Randomized, Placebo-Controlled Study.
Konstantinovic LM, Kanjuh ZM, Milovanovic AN, Cutovic MR, Djurovic AG, Savic VG, Dragin AS, Milovanovic ND
Efficacy of low-level laser therapy in the management of neck pain: a systematic review and meta-analysis of randomised placebo or active-treatment controlled trials.
Chow RT, Johnson MI, Lopes-Martins RA, Bjordal JM
Nerves and Pain Nerve Inhibition
Pre-Irradiation of blood by gallium aluminum arsenide (830 nm) low-level laser enhances peripheral endogenous opioid analgesia in rats.
Hagiwara S, Iwasaka H, Hasegawa A, Noguchi T
Nerves and Pain Nerve Regeneration
Laser phototherapy (780 nm), a new modality in treatment of long-term incomplete peripheral nerve injury: a randomized double-blind placebo-controlled study.
Rochkind S, Drory V, Alon M, Nissan M, Ouaknine GE
Optically mediated nerve stimulation: Identification of injury thresholds.
Wells JD, Thomsen S, Whitaker P, Jansen ED, Kao CC, Konrad PE, Mahadevan-Jansen A
Effects of diode laser therapy on the acellular dermal matrix.
Soares LP, de Oliveira MG, de Almeida Reis SR
Role of nitric oxide in the visible light-induced rapid increase of human skin microcirculation at the local and systemic levels: II.
Samoilova KA, Zhevago NA, Petrishchev NN, Zimin AA
High-Intensity Laser and Photodynamic Therapy as a Treatment for Recurrent Herpes Labialis
Marotti J, Sperandio FF, Fregnani ER, Aranha AC, de Freitas PM, de Paula Eduardo C
Effects of Low-Level Laser Therapy on Pain and Scar Formation after Inguinal Herniation Surgery: A Randomized Controlled Single-Blind Study.
de Paiva Carvalho RL, Alcântara PS, Kamamoto F, Cressoni MD, Casarotto RA
In Vivo Effects on the Expression of Vascular Endothelial Growth Factor-A(165) Messenger Ribonucleic Acid of an Infrared Diode Laser Associated or Not with a Visible Red Diode Laser.
Silva TC, Oliveira TM, Sakai VT, Dionísio TJ, Santos CF, Bagnato VS, Machado MA
The Effect of Equal Daily Dose Achieved by Different Power Densities of Low-Level Laser Therapy at 635 and 670 nm on Wound Tensile Strength in Rats: A Short Report.
Vasilenko T, Slezák M, Kováč I, Bottková Z, Jakubčo J, Kostelníková M, Tomori Z, Gál P.
Effect of Low-Level Laser Therapy and Calcitonin on Bone Repair in Castrated Rats: A Densitometric Study.
Nascimento SB, Cardoso CA, Ribeiro TP, Almeida JD, Albertini R, Munin E, Arisawa EA.
Low Level Laser Treatment of Tendinopathy: A Systematic Review with Meta-analysis.
Tumilty S, Munn J, McDonough S, Hurley DA, Basford JR, Baxter GD.
Effect of laser acupoint treatment on blood pressure and body weight-a pilot study.
Zhang J, Marquina N, Oxinos G, Sau A, Ng D.
Comparison of splinting and splinting plus low-level laser therapy in idiopathic carpal tunnel syndrome.
Yagci I, Elmas O, Akcan E, Ustun I, Gunduz OH, Guven Z.
Reduced axonal transport in Parkinson’s disease cybrid neurites is restored by light therapy.
Trimmer PA, Schwartz KM, Borland MK, De Taboada L, Streeter J, Oron U.
The effect of low-level laser in knee osteoarthritis: a double-blind, randomized, placebo-controlled trial.
Hegedus B, Viharos L, Gervain M, Gálfi M.
Low level laser therapy in acute dehiscence saphenectomy: therapeutic proposal.
Pinto NC, Pereira MH, Stolf NA, Chavantes MC.
Low-intensity laser radiation in the combined treatment of patients with chronic obstructive bronchitis
Kashanskaia EP, Fedorov AA.
The use of low-level light for hair growth: part I.
Avram MR, Rogers NE.
The application of low-level laser therapy after cesarean section does not compromise blood prolactin levels and lactation status.
Mokmeli S, Khazemikho N, Niromanesh S, Vatankhah Z.
Relationship between laser acupuncture analgesia and the function of mast cells
Cheng K, Shen XY, Ding GH, Wu F.
Effect of low-level laser therapy on the fracture healing process.
Kazem Shakouri S, Soleimanpour J, Salekzamani Y, Oskuie MR.
Increase of neuronal sprouting and migration using 780 nm laser phototherapy as procedure for cell therapy.
Rochkind S, El-Ani D, Nevo Z, Shahar A.
Impact of low-intensity laser on the suppression of infections caused by Herpes simplex viruses 1 and 2: in vitro study
Ferreira Dde C, Martins FO, Romanos MT.
Laser therapy of painful shoulder and shoulder-hand syndrome in treatment of patients after the stroke.
Karabegović A, Kapidzić-Duraković S, Ljuca F.
Stem cell proliferation under low intensity laser irradiation: a preliminary study.
Eduardo Fde P, Bueno DF, de Freitas PM, Marques MM, Passos-Bueno MR, Eduardo Cde P, Zatz M.